Date of Award
8-5-2020
Document Type
Open Access Thesis
Degree Name
MS in Physician Assistant Studies (PA)
Department
Physician Assistant Studies
First Advisor
Vanessa Bester, EdD, PA-C
Abstract
In this retrospective review, the use of extracorporeal cardiopulmonary resuscitation (ECPR) using extracorporeal membrane oxygenation (ECMO) was assessed in the management of refractory ventricular fibrillation (VF) and ventricular tachycardia (VT) out-of-hospital cardiac arrest (OHCA). Multiple factors were evaluated such as the duration of manual or mechanical cardiopulmonary resuscitation (CPR), ECPR protocols and the rate of favorable neurologic outcomes for these OHCA patients. Survival with a favorable neurologic outcome is defined as cerebral performance categories (CPC) 1 or 2. Although CPR remains and will continue to be a critical component in the management of cardiac arrest, the persistently high mortality rate of the condition warrants further intervention. Established ECPR protocols include timely administration of emergency intervention, patient inclusion and exclusion criteria, mechanical CPR, specific cannulation technique, percutaneous coronary intervention (PCI), as well as post-catheterization lab management. These protocols have shown encouraging initial results with an increased rate of survival with a favorable neurologic outcome when compared to management of similar patients with conventional CPR alone. This literature review found that there is strong evidence supporting the use of ECPR with ECMO support in the management of refractory VF/VT OHCA. Although there exists the need for more randomized control trials, implementation of ECMO and ECPR programs have shown to improve neurological outcomes for these patients.
Identifier
SC 11.PAS.2020.Lund.T
Recommended Citation
Lund, Timothy, "Does the Use of Extracorporeal Cardiopulmonary Resuscitation Improve Neurologically Favorable Survival in Patients with Refractory Out-of-Hospital Cardiac Arrest?" (2020). Theses and Graduate Projects. 1063.
https://idun.augsburg.edu/etd/1063