Date of Award

8-12-2020

Document Type

Open Access Thesis

Degree Name

MS in Physician Assistant Studies (PA)

Department

Physician Assistant Studies

First Advisor

Amanda Perkins, Pharm D

Abstract

In this retrospective review, metabolic factors present in diabetic patients who underwent bariatric surgery were compared against those who were treated with medical therapy alone. These factors include: diabetes remission, glycosylated hemoglobin levels, medication use, changes in beta cells function, insulin sensitivity, incretin levels, weight loss, lipid profiles and blood pressures. Following bariatric surgery, patients observed superior changes in diabetes remission rates, glycosylated hemoglobin levels, medication use, beta cell function, insulin sensitivity, incretin levels, and weight loss when compared to those who were treated with medical therapy alone. Blood pressure changes were not significantly different among the two treatment groups. Between 3-5 years after surgery, the surgical group showed significantly lower levels of low-density lipoproteins, total cholesterol, and triglycerides. In addition, high density lipoprotein values were raised in greater amounts following bariatric surgery. Diabetic patients who undergo bariatric surgery report higher amounts of minor complications following surgery than those who are not diagnosed with diabetes. This paper also examined the side effects and safety of bariatric surgery to determine associated risks and benefits. Nutritional deficiencies, bone metabolism, dumping syndrome, and surgical complications should be considered potential risk factors by patients who are considering bariatric surgery to treat their diabetes. Benefits following surgery include a decreased death rate from coronary artery disease, diabetes, and cancer.

Identifier

SC 11.PAS.2020.Thornley.D

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