Date of Award


Document Type

Open Access Thesis

Degree Name

MS in Physician Assistant Studies (PA)


Physician Assistant Studies

First Advisor

Alicia Quella


Dengue virus is the most common mosquito born disease worldwide and is an endemic infection in many tropical and subtropical habitats, especially areas where poor public health infrastructure makes it difficult to control. According to the Centers for Disease Control and Prevention (CDC), the dengue virus is a leading cause of febrile illness among travelers returning from Latin America. The dengue virus is a member of the family Flaviviridae and is transmitted to humans by the vector Aedes mosquitos, most frequently the Aedes aegypti mosquito, and secondarily by Aedes albopictus. Dengue infection results in a spectrum of clinical disease, ranging from asymptomatic to death. Infection with dengue virus is a significant global health challenge as an estimated 390 million infections occur annually. The number of annual infections continues to rise, with the reason for this growth being multifactorial. Suspected factors playing a role include climate change, urbanization, population growth, poor sanitation, poor public health infrastructure, international travel, international trade, precipitation, and geographic mosquito expansion. In recent years, autochthonous dengue cases have even been reported in the United States; a region which had not seen reports of dengue for 75 years.


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