Date of Award
Open Access Thesis
MS in Physician Assistant Studies (PA)
Physician Assistant Studies
Eric Van Hecke, MPAS, PA-C, CAQ-EM, DMSC candidate
Background: Cardiovascular disease is one of the leading causes of morbidity and mortality in humans worldwide. Ventricular remodeling following a myocardial infarction leads to detrimental outcomes due to cardiovascular death and ventricular dysfunction. Exercise training is an adjunct strategy to reduce the myocardial remodeling process.
Purpose: The paper seeks to answer the following PICO question: P: Population with post- infarct myocardial-remodeling I: Exercise following a myocardial infarction C: Sedentary approach O: Prevention of deleterious myocardial remodeling post-MI
Methods: A comprehensive literature review was done using PubMed and Science Direct with articles published in 2019 or after. The search was conducted using the terms: myocardial remodeling exercise, post-infarct ventricular remodeling, post-infarct myocardial remodeling exercise, post-infarct myocardial remodeling, and myocardial remodeling training. Peer- reviewed articles and scholarly journals were included in the search.
Conclusions: Studies in which exercise was introduced following a myocardial infarction have demonstrated a reduction in cardiac remodeling and an improvement in overall cardiac function. These findings suggest that an exercise program following a myocardial infarction can benefit patients in reducing negative complications such as cardiac wall thinning, infarct expansion, and heart failure.
Gladis, Vladislav, "Systematic review of the effect of exercise on the reduction of myocardial remodeling following a myocardial infarction compared to a sedentary approach" (2023). Theses and Graduate Projects. 1572.