Date of Award


Document Type

Restricted Access Thesis

Degree Name

MS in Physician Assistant Studies (PA)


Physician Assistant Studies

First Advisor

Vanessa Bester, EdD. PA-C


Background: Psychosis is a prominent mental illness prevalent in our society. Social determinants factor into effect the diagnosis, prevention, and treatment of psychosis. For the best outcomes for individuals suffering from psychosis identifying those social determinants is essential.

Purpose: Social determinants negatively impact the onset, progression, and treatment of psychosis. Figuring out the role specific social determinants have on psychosis can further prevention and continuity of care. This literature review intends to figure out specific social determinants of health that effect the diagnosis, prevention, and treatment of psychosis.

Methods: A comprehensive literature review was conducted using Pub Med using the search terms social determinants of health, psychosis.

Conclusions: Neighborhood determinants such as the racial composition of a neighborhood, neighborhood disruption, and instability were found to increase the likelihood of developing psychosis. Childhood trauma negatively impacts the expression comorbid conditions related to psychosis such as diabetes and adipose dysregulation. Childhood trauma and stress negatively impact the development and management of psychosis. Specific markers were found to be associated with psychosis. Future research should focus on incorporating biomarkers and biosocial markers with social determinants of health, and methods to increase mental healthcare access to immigrants and minority populations.


SC 11.PAS.2022.Amanor.V