Date of Award


Document Type

Open Access Thesis

Degree Name

MS in Physician Assistant Studies (PA)


Physician Assistant Studies

First Advisor

Ryane Lester, PA-C


Background: Cardiovascular disease remains one of the leading causes of death worldwide. Intermittent fasting is a unique intervention that is beginning to be studied more extensively for weight loss, positive alterations in serum lipid profile, and improvement of insulin resistance which are all modifiable risk factors for the development of cardiovascular disease.

Purpose: The research question at the center of this literature review is: does the addition of intermittent fasting reduce the risk of developing cardiovascular disease? The reduction of cardiovascular disease was studied through alterations in weight, cholesterol, and diabetic labs.

Methods: A comprehensive literature review was conducted using academic search premier ultimate and pubmed using the search terms intermittent fasting, time restricted feeding, weight loss, lipid profile, diabetes, and insulin resistance. Inclusion criteria were primary studies that were published within the last 5 years. Exclusion criteria were review articles and primary studies published prior to 2017.

Conclusions: Intermittent fasting may aid in reductions of modifiable risk factors for developing cardiovascular disease including body weight, dyslipidemia, and insulin resistance. More research consisting of large, randomized controlled trials is necessary to reproduce the results to incorporate intermittent fasting into medical guidelines.


SC 11.PAS.2022.DeKam.E

Included in

Cardiology Commons